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Host Lisa Simeone talks to reporter Joshua Levs at member station W-A-B-E in Atlanta, about yesterday's military plane crash that killed 21 members of the Air National Guard. Flight data recorders have been recovered, but the recovery of victims has been hampered by poor weather conditions.

NPR'S Brian Naylor reports on the recent improvements in Washington D.C.'s economy and government. But while many are pleased, some say the District of Columbia still has a long way to go.

Host Lisa Simeone speaks with Thomas Hayden, who donated some genetic material to the Human Genome Project, and who wrote an essay in today's New York Times magazine.

Liane reads letters from listeners. (2:45).

A consortium of AIDS drug makers is suing the South African government, trying to block a law they say will erode their patent rights...and their profits. The law would allow the government to import generic drugs or authorize their manufacture, if needed drugs are priced too high. AIDS activists want the government to implement the law, so that the estimated four million infected with H-I-V will have access to life-sustaining drugs. NPR's Brenda Wilson reports from Johannesburg.

More letters from listeners who suggest some ways that everyday items could be better designed.

The state of California is considering buying more than 30-thousand miles of high voltage power transmission lines. Governor Gray Davis sees the move as a way to help solve the state's power crisis, by federal regulators are not so sure. From member station KPCC in Los Angeles, Rachael Myrow reports.

Weekend Edition's resident satirists at the Montana Logging and Ballet Company have some "common sense solutions" for the problems the President has experienced in competing for the nation's attention.

NPR's Gerry Hadden reports that the largest concentration of Zapatistas in Mexico isn't in the jungles of Chiapas, but rather in Mexico City. Zapatistas are indigineous to Mexico and have been fighting since 19-94 for more rights. Right now, a caravan of Zapitistas from Chiapas -- a so-called caravan of peace -- is headed to Mexico City to help further their cause. And Zapitistas in the capital hope it will shed light on their particular urban problems.

Host Melissa Block talks with Swedish musician and New Orleans resident Anders Osborne about his new album, Ash Wednesday Blues. Osborne used to travel all over the world, but now he wanders from genre to genre in his music. Featuring the Dirty Dozen Brass Band's sousaphone player, his roots-rock is influenced by the lively and diverse music scene of New Orleans clubs.

Film critic Kenneth Turan reviews Memento, the latest work by independent film-maker Christopher Nolan. The plot revolves around a man who has no short-term memory, and who's trying to avenge his wife's murder. In order to remember what he learns about the murder he writes countless lists, and even goes so far as to tattoo key information on his body. So far, the movie has won critical acclaim and a screen-writing award from the Sundance Film Festival.

Host Melissa Block talks with John Tiscornia , owner of Lyndeth Howe Country House Hotel, in Cumbria, England. His small bed-and-breakfast business has suffered great losses in recent weeks, since tourists have shied-away from the foot-and-mouth infected regions of the English countryside.